PLC sandwich Another genius bit of biological design comes from the enzyme PLC. PLC is a phospholipase whose job it is to cleave of the headgroup of PI(4,5)P2, a membrane lipid. Like tethering proteins, PLCs are made up out of a couple of domains. At its core there are three domains. There is the catalyticContinue reading “PLC sandwich”
Category Archives: Lipids
Tethered to science
Tethered to science For a long while I haven’t posted anything, being too tired and work got in the way. Then after combing back from a conference and a break late February, full of ideas but no energy to work them out, I turned to my GP. There I was told I was overworked, warnedContinue reading “Tethered to science”
Giving a talk
Giving a talk When preparing to give a talk about your work you always need to make lots of decisions. One is about the amount of background vs results. Ideally you would like to have lots of time to discuss your new results, but for the audience to place them into context, or to understandContinue reading “Giving a talk”
What makes a binding domain
What makes a binding domain One of the projects that I am busy with at the moment is writing a review about phosphoinositide binding domains. Preparing for that I have been reading old reviews on the same topic. One thing that I noticed was that some domains which have shown to bind phosphoinositides, like theContinue reading “What makes a binding domain”
Plant en Zo 