Protein – Plant en Zo

Regulating enzymes

Regulating enzymes Regulation can happen in many ways. For metabolic pathways three main regulatory mechanisms can be distinguished. A) The production of its enzymes, B) the degradation of these enzymes and C) regulating the activity of these enzymes. Where the regulation through the production and degradation of enzymes is crude and imprecise, regulation through regulatingContinue reading “Regulating enzymes”

Gene expression ≠ protein accumulation

Gene expression ≠ protein accumulation I was remined lately that people forget that gene expression does not equal protein accumulation. And also that protein accumulated is not equal to protein that is actual able to do what it is made for. So here an explaination about gene expression, protein accumulation, why are they not the same,Continue reading “Gene expression ≠ protein accumulation”

PLC sandwich

PLC sandwich Another genius bit of biological design comes from the enzyme PLC. PLC is a phospholipase whose job it is to cleave of the headgroup of PI(4,5)P2, a membrane lipid. Like tethering proteins, PLCs are made up out of a couple of domains. At its core there are three domains. There is the catalyticContinue reading “PLC sandwich”

Tethered to science

Tethered to science For a long while I haven’t posted anything, being too tired and work got in the way. Then after combing back from a conference and a break late February, full of ideas but no energy to work them out, I turned to my GP. There I was told I was overworked, warnedContinue reading “Tethered to science”